8 results
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... free fatty acid metabolism ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... #pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... transport chain and inhibits ... hepatocellular aerobic ATP ... also includes symptoms ... Toxicology #Diagnosis #Management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
pyrophosphate: Inhibitor ... • Pernicious anemia ... mineralization Symptoms ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Syndrome - Metabolic ... PO4 -> decr RBC ATP ... hemolysis - anemia ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... Riluzole - An inhibitor ... neurology #diagnosis #management
Rickets and Osteomalacia: Pathogenesis and Clinical Findings
 • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Calcification inhibitors ... enzymes (like ALP ... Abnormal Vitamin D Metabolism ... #diagnosis #signs ... #symptoms
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... and Symptoms: ... - Cytopenias (anemia ... Pathophysiology ... therapies: JAK inhibitors
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
Cerebral Atrophy and Metabolic ... lymphocytosis, mild anemia ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry