14 results
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
#Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
#Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... transport chain and inhibits ... also includes symptoms ... Toxicology #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... postpartum): • Initial symptoms ... Liver #Pregnancy #hepatology ... #pathophysiology
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... : • ACE Inhibitors ... heartfailure #diagnosis #management ... #cardiology #pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Pheochromocytoma - Diagnosis and Management Summary
10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
and Signs: 50% ... and signs: • ... leukocytosis, psychiatric ... monoamine oxidase inhibitors ... in carbohydrate metabolism
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
m/s • Other signs ... Phosphodiesterase-5 inhibitors ... through reduced cGMP metabolism ... Hypertension #diagnosis #management ... #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
pyrophosphate: Inhibitor ... collection with EDTA Pathophysiology ... mineralization Symptoms ... Nephrolithiasis • Metabolic ... Hyophosphatasia #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... Riluzole - An inhibitor ... neurology #diagnosis #management