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diagnosis differential algorithm liver antiphospholipid apls ascites centralretinalartery cholangitis cirrhosis crao enzymes gap globulin hepatitis hypercoagulable hypertension injury leukostasis lfts
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... cholangitis #diagnosis #workup ... #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... and hepatorenal syndrome ... • Budd Chiari syndrome ... pregnancy • Primary biliary ... #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... concentration (bowel or biliary ... Jcortesizaguirr #Ascites #workup ... Differential #Diagnosis #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... The presence of metabolic ... syndrome criteria ... include extrahepatic biliary ... #Algorithm #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... Shock liver • Metabolic ... • Gilbert's syndrome ... diagnosis #algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... : • Pathophysiology ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... #diagnosis #hematology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
congenital defects) -> Abnormal ... anti-coagulation • Hematologic ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... maternal chromosomal causes ... Hypercoagulable #Workup ... Algorithm #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... chain assay • An abnormal ... differential #diagnosis #hematology
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