58 results
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Glycol Toxicity #Pathophysiology ... #Toxicology #EthyleneGlycol ... #Metabolism #Fomepizole
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... also includes symptoms ... of metabolic acidosis ... LacticAcidosis #Toxicity #Toxicology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... Cyanide #Toxicity #Toxicology ... #Pathophysiology ... #Management #Treatment
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... ingestion/exposure Symptoms ... Labs: Anion-Gap Metabolic ... Aspirin #Toxicity #Toxicology ... diagnosis #management #Treatment
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... effect on negative symptoms ... - Metabolism - ... #Clozapine #Toxicology
Carbon Monoxide Poisoning

Symptoms are non-specific:
 - Headache 90%
 - Nausea/vomiting 50%
 - Vertigo 50%
 - Altered
Monoxide Poisoning Symptoms ... Outdoors improves symptoms ... Treatment: 100% ... Monoxide #Poisoning #Toxicology
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Renal failure • Metabolic ... Colchicine #Toxicity #Toxicology ... #Symptoms #Signs
Salicylate metabolism.
#Pathophysiology #Metabolism #Toxicology #Salicylate #Aspirin
Salicylate metabolism ... #Pathophysiology ... #Metabolism #Toxicology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... postpartum): • Initial symptoms ... diagnosis #management #pathophysiology
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... Acetaminophen #APAP #metabolism ... #toxicity #Toxicology ... #Pathophysiology