21 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
causes spinal cord ... While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... #Pediatrics #Peds
Pediatric Acute Abdominal Pain - Differential Diagnosis Algorithm
Generalized/Migratory:
 • Intussusception
 • Gastroenteritis
 • Viral Illness
 •
Pediatric Acute ... - Differential Diagnosis ... Algorithm Generalized ... Gastroesophageal Reflux ... #Peds #Pediatrics
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
sensitivity to cold ... the ankle jerk reflex ... evaluation confirmed a diagnosis ... #Delayed #Clinical ... #Video #Neurology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... bladder and rectal reflex ... Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... , sleep apnea, cor ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Pediatric Vomiting - Gastrointestinal and Systemic Causes - Differential Diagnosis Algorithm
Hepatobiliary:
 • Acute Hepatitis
 • Acute
Pediatric Vomiting ... - Differential Diagnosis ... Algorithm Hepatobiliary ... Gastroesophageal Reflux ... #Peds #Pediatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... • Symptoms and signs ... dysfunction • Abnormal reflexes ... differential #algorithm
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds ... #pediatrics
Primitive Suck, Rooting Reflex on Newborn Physical Exam 
The normal response to stroking the lateral aspect
Suck, Rooting Reflex ... foot then a grasp reflex ... toes or “Babinski sign ... #PhysicalExam #clinical ... #video #peds #pediatrics