20 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
• NAFLD • Cirrhosis ... Hepatopathy • Acute ... 1000): • DILI (Drug-induced ... ) • Non-hepatic ... Differential #Diagnosis #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
or secondary to cirrhosis ... fibrosis, Drugs ... 3) Sinusoidal: Cirrhosis ... , Polycystic liver ... diagnosis #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Viral • Drugs ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Clues to non-cirrhotic ... /acute hepatitis ... sarcoidosis) • Liver ... metastasis • Fatty liver ... Diagnosis #causes #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... Hepatitis (AAH) Drug-Induced ... #Failure #Cirrhosis ... #Hepatology #gastroenterology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... , Recreational Drugs ... Vasculature • Hepatic ... Congestion/CHF • Hepatic ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... disease, Hepatic ... dechallenge • Acute ... presentation: Hepatic ... Diagnosis #Algorithm #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... 15X ULN - Drugs ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... ) • Advanced Liver ... catastrophes, Acute ... Deficiencies #Summary #table ... comparison #diagnosis #hematology