11 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis - Summary ... ) is an autoimmune-mediated ... neurodegenerative disease ... • Or brainstem syndromes ... Multiple Sclerosis Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... solid cancers • Autoimmune ... diseases: SLE++ ... Unknown cause Treatment ... #summary #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs ... #symptoms #rheumatology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Unilateral • Signs ... - Typical MS-like ... other auto-immune diseases ... #rheumatology # ... ophthalmology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management Summary ... Pathophysiology ... the result of an autoimmune ... Treatment: • ... Baclofen • Severe Disease
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... be any age) Autoimmune ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... #Rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management Summary ... sex • Metabolic syndrome ... double contour sign ... +Radiographic signs ... #rheumatology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
mesothelioma, etc - Autoimmune ... , Lyme disease, ... cell lymphoma Pathophysiology ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Malignancies ▪ Autoimmune ... diseases (often ... Presentation • Common Signs ... Pathophysiology ... Infections, malignancy, autoimmune