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testing diagnosis fecal fobt laboratory occultblood accuracy betadglucan cobalamin deficiency differential falsenegative falsenegatives falsepositive fungal galactomannan inaccurate management nutrition sensitivity
What is Fecal Occult Blood Testing (FOBT) • Screening for colorectal cancer in average risk population
setting - Guaiac ... Testing #FOBT #Guaiac ... #FalsePositives
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... who don't take B12 ... - Low Vit B12 ... level (< 200 pg
Causes of Inaccurate Fecal Occult Blood Test Results False Positive gFOBT: Ingestion of nonhuman heme (eg, meat
medication #Guaiac ... Testing #Laboratory #FalsePositive
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Mucormycosis • Neg (<60 pg ... Fungal #Testing #FalsePositives
Cobalamin (vitamin B12) In the diet: 5-15 pg/day (min. 1-5) B12 Protein HC pH t B12 Duodenum Stomach 1 B12 R-protein Protein From saliva R-protein Intrinsic factor Pancreas B12 R-Protein Trypsin B12 Terminal ileum B12 IF 2 Specific binding to receptors of
Cobalamin (vitamin B12 ... the diet: 5-15 pg ... day (min. 1-5) B12 ... Protein HC pH t B12 ... IF B12 pH >
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