11 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... patches on the skin ... endocrinology #diagnosis #signs
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
hypotension - Nausea ... nervous system symptoms ... disorders: - Pale skin ... Insufficiency #Signs ... #Symptoms #Adrenal
Differentiating Features Between Central and Peripheral Cyanosis

Mechanism - Arterial destauration
Sites - Skin, mucous membrane of oral
destauration Sites - Skin ... therapy - Pulmonary cause ... Sites - Only skin ... Central #Peripheral #Comparison ... #Signs #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... 21-OHD in the adrenal ... as "congenital adrenal ... Signs/Symptoms/Complications ... cold & mottled skin
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
, and possibly renal ... are not caused ... nodes: 13-15%, skin ... anterior/posterior MSK ... Diagnosis #Management #Signs
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... Diagnosis #Clinical #Photo
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
easily bruisable skin ... the abdomen for adrenal ... tumors • The adrenal ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... • Urinalysis (Renal
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... tract, and often causes
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... bone formation MSK ... Skull expansion causes ... pathophysiology #diagnosis #signs ... #symptoms #complications