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diagnosis management signs symptoms erythematosus hematology lupus sle arteritis autoinflammatory behcet chronic classification cll colitis cryofibrinogenemia cryoglobulinemia cryoglobulins derm dermatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... - Purpura - Skin ... : • Clinical triad ... reticularis & skin ... classification #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... nose chondritis, skin ... recurrent fevers, vasculitis ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... Diagnosis = clinical ... required due to skip ... Treatment of GCA ... them, but urgent rheumatology
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
eosinophilia and systemic ... symptoms (DRESS ... Churg-Strauss syndrome ... #dermatology #clinical ... #photo
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... processes: • Systemic ... Diagnosis: • + Clinical ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Non-autoimmune rheumatologic ... Clinical Features ... Seizures • Strokes Skin
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... ) • Cutaneous vasculitis ... Vasculitis: • ... Adenocarcinoma Treatment ... #Rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Orange or Hep C Clinical ... Hepatomegaly • Skin ... ’s CLL Scoring system ... microglobulin Treatment
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