10 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... • Ocular: uveitis ... #AdultOnset #Stills ... #management #treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... response to local skin ... Arthritis, AS Treatment ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Skin manifestations ... refractory lesions Ocular ... #Syndrome #Treatment ... #management #pharmacology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... A nonpruritic macular ... maculopapular skin ... Treatment - Mild ... #rheumatology #management
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
weight loss • Skin ... Albuminuria, nephrotic syndrome ... meningovascular disease ... Coronary artery disease ... stages #diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... sites such as the collar ... and lower jaw Treatment ... disease. ... Rheumatology #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... gland) biopsy • Ocular ... amyloidosis, PAH Skin ... Adenocarcinoma Treatment ... Rheumatology #Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
osteomyelitis or skin ... organism into the skin ... osteoarticular, pulmonary, ocular ... Mouth, throat, skin ... Fungal #Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... cavitating pneumonia, skin ... lesions, ocular ... Differential #Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
chondritis • Ocular ... • Inner ear • Skin ... Sarcoidosis • Behcet disease ... affected tissue Treatment ... rheumatology #diagnosis #management