10 results
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin ... Vasculitis Skin ... Vasculitis: • Behcet Disease ... • Cogan syndrome ... #dermatology #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Goodpasture syndrome ... • Giant cell arteritis ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Tumor-associated ... - SLE Neurologic ... Scleroderma Thickened skin ... Lymphadenopathy • Tumor-associated ... differential #diagnosis #rheumatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... injury) • Neurologic ... myocarditis, coronary arteritis ... interferon alfa, or tumor ... signs #symptoms #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
GCA (Giant Cell Arteritis ... , neurologic, and ... cognitive impairment, neurologic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... lysis syndrome: ... CLL -> Invade Skin ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... changes (POEMS syndrome ... (RA, Temporal arteritis ... gastric tumors • Hematology ... differential #diagnosis #hematology
Blanching Spider Angioma (Nevus) on Physical Exam

Spider angiomas are usually benign but often can be suggestive
underlying systemic disease ... just beneath the skin ... telangiectasia #PhysicalExam ... #clinical #video ... #dermatology #skin