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diagnosis differential rheumatology clinical oncology vasculitis allergy angioma blanching causes conditions cutaneous dermatologic effusions extrarticular gap globulin gpa granulomatosis immunology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Involving the Skin ... Vasculitis: • Behcet ... Disease • Cogan ... syndrome #Cutaneous ... #dermatology #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... injury) • Neurologic ... myocarditis, coronary arteritis ... interferon alfa, or tumor ... signs #symptoms #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... • Goodpasture syndrome ... • Giant cell arteritis ... vasculitis #Dermatologic ... Polyangiitis #GPA #dermatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Tumor-associated ... - SLE Neurologic ... Scleroderma Thickened skin ... Lymphadenopathy • Tumor-associated ... differential #diagnosis #rheumatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... syndrome, caused ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
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 Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
arthritis - SLE - Behcet ... Seronegative Reactive Syndrome ... Effusions: - Hematologic ... - Giant cell tumor ... diagnosis #msk #physicalexam
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
GCA (Giant Cell Arteritis ... , neurologic, and ... cognitive impairment, neurologic ... vasculitis • Behcet ... syndrome: Recurrent
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... lysis syndrome: ... CLL -> Invade Skin ... #Leukemia #Hematology
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
following: • Behcet ... Disease • Pyoderma ... (PG) • Sweet syndrome ... • Blind loop syndrome ... allergy #immunology #dermatology
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