13 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... • Clinically ... Relevant HES Variants ... #HES #Hematology ... eosinophils #diagnosis #management
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #nonpalpable #dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
, caused by the ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical ... #SJS #skin
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Causes of Antibiotic ... Failure - Differential ... NMS, serotonin syndrome ... Soon: Can take 48 hrs ... effect/reaction (ie SJS
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
and Management ... than 1500 and clinical ... blood eosinophilia Secondary ... Causes: - Allergic ... #differential #
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
thought to be secondary ... carotid sinus syndrome ... syncope (ruling out differential ... further guide management ... should be guided by clinical
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Resolution > 15 days Differentials ... drug reaction • SJS ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Orbital Apex Syndrome secondary to Herpes Zoster Ophthalmicus (HZO)

This 81 yo male was referred to our
secondary to Herpes ... other potential causes ... secondary to Herpes ... Ophthalmicus #HZO #clinical ... ophthalmology #physicalexam
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... to 8 years Clinical ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome