12 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Defects Bernard-Soulier ... Syndrome • Defect ... MYH9-Related Disorder ... #table #differential ... #diagnosis #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... with qualitative defects ... considered first-line ... #disorders #hematology ... #diagnosis #Aggregometry
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... - Quantitative Defect ... Platelet Function ... - Qualitative Defect ... #Causes #Hematology
Nail diseases and disorders.
 - Spoon Nails (Koilonychia)
 - Pitting of Nails
 - Beau's Lines
 -
Nails - Beau's Lines ... white spots) #Diagnosis ... #Differential # ... #Leukonychia #Table ... #Clinical #PhysicalExam
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #nonpalpable #dermatology
Platelet Disorders - Differential Diagnosis Framework

Qualitative Defects:
 • Adhesion
 • Aggregation
 • Secretion

Quantitative Defects:
 • Production:
Platelet Disorders ... - Differential ... Diagnosis Framework ... #Disorders #Differential ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... diverse genotypes): SS ... with or without platelet ... Consider RBC membrane disorder ... #workup #hematology
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
lesion parallel to lines ... palms/soles - Differential ... diagnosis: secondary ... rosea #clinical #dermatology ... #photo #PhysicalExam
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential ... Thrombocytopenia - Abnormal platelet ... Vasculitis - Collagen disorders ... #Causes #dermatology ... #physicalexam
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
macule and papule (Table ... diagnosis; however ... diagnosis, which ... pathognomonic for SJS ... #Diagnosis #Dermatology