11 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... Management • ... adsorption onto cancer ... #Diagnosis #Management ... #treatment #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... Differential Diaqnoses ... hemopathies, solid cancers ... #management #treatment ... #rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Lymphoma or other cancers ... gastric and breast cancer ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... to a diffusion-perfusion ... radioactive lung perfusion ... #diagnosis #management ... #treatment #hepatology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
thermoregulatory center ... ; Serotonin syndrome ... loss from the skin ... #Hyperthermia #comparison ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... workup #oncology #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Headaches • Pale skin ... Constitutional Syndromes ... Anemia #oncology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Diagnosis: • Dry ... thickening or effusion ... Nephrogenic DI Hematologic ... Diagnosis #Management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• Tumor lysis syndrome ... lymphoid organs When Cancer ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
gammopathy, and skin ... changes (POEMS syndrome ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology