15 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Aseptic necrosis of hip ... Demyelinating syndromes ... ) Blood (75%): Anemia ... #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Clinical Presentation ... - HCV - HIV ... #oncology #hematology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... lymphopenia, low PLT • Anemia ... #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
workup 1) Clinical ... hydrocephalus, HIV ... - Progressive amnesia ... Aphaso-apraxo-agnosia syndrome ... #Geriatrics #Workup
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... HBV infection, HIV ... Labs/Diagnosis: ... (e.g. systemic lupus ... classification #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... Mycoplasma, EBV, HIV ... #hematology #diagnosis
Newborn Infant - Routine Examination

Birthweight, gestational age and birthweight percentile are noted.
General observation Of the baby's
When the diagnosis ... until last as the procedure ... Newborn #Infant #PhysicalExam ... Examination #Peds #Pediatrics ... #Diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... autoimmune hemolytic anemia ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... , HIV) • Glucocorticoid
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Agent Orange or Hep ... C Clinical Presentation ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... • Richter’s Syndrome