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Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... • < 30,000 and bleeding ... postoperative bleeding ... < 100,000 and bleeding ... Platelet transfusions
Forrest Classification for Peptic Ulcer Bleeding Rebleeding risks are without endoscopic intervention 1a - Spurting Bleed - 60-100%
Forrest Classification ... Bleed - 60-100% Re-bleeding ... Bleed - 50% Re-bleeding ... IIa - Non-Bleeding ... #Forrest #Classification
Forrest Classification for Describing Endoscopic Findings in Patients With Bleeding Ulcers and Predicting Risk of Rebleeding Classification
Forrest Classification ... Classification ... Diet I Active bleeding ... II Stigmata of bleeding ... diet #Forrest #Classification
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
A Classification of Coagulation Disorders #Coagulation #Disorders #Classification #Platelet #Classification #Differential #Diagnosis
A Classification ... Coagulation #Disorders #Classification ... #Platelet #Classification
Thresholds for Transfusion of Platelets in Adults Major surgery or invasive procedure, no active bleeding - ≤
Transfusion of Platelets ... procedure, no active bleeding ... neurosurgery, no active bleeding ... Surgery with active bleeding ... #Management #Platelets
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 Forrest Classification of Upper GI Bleeding Acute Hemorrhage Ia - Active Spurting, Re-bleeding Risk 60-100%
Forrest Classification ... of Upper GI Bleeding ... Active Spurting, Re-bleeding ... Active Oozing, Re-bleeding ... enrrikke #Forrest #Classification
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... vs Acquired • Platelet ... vs Acquired #Bleeding
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Usually normal platelet
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