5816 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... #differential #diagnosis
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... Platelet Count ... #Differential #Diagnosis ... #causes #Platelets
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
children) • Platelets ... extremely low platelet ... Thrombocytopenia #Diagnosis
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... Management #treatment #diagnosis
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... TEG #Management #Diagnosis
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... #differential #diagnosis
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastography #diagnosis
Causes of Acquired Platelet Dysfunction

#Acquired #Platelet #Dysfunction #Causes #differential #Diagnosis #hematology
Causes of Acquired Platelet ... #Acquired #Platelet ... #differential #Diagnosis
Thrombocytopenia 
Work up, differential diagnosis and management.

Satyendra Dhar MD, @DharSaty

#thrombocytopenia #platelets #ITP #DIC
, differential diagnosis ... thrombocytopenia #platelets
Causes of Thrombocytopenia.
Platelet counts may be depressed because of decreased production or due to increased platelet
Platelet counts ... due to increased platelet ... #Diagnosis #Hematology