130 results
Formation of a Hemostatic Platelet Plug

#Hemostatic #Platelet #Plug #Formation #Pathophysiology #Hematology
of a Hemostatic Platelet ... #Hemostatic #Platelet ... Plug #Formation #Pathophysiology ... #Hematology
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
children) • Platelets ... extremely low platelet ... Diagnosis #Overview #Hematology
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis Platelet ... Diagnosis #causes #Platelets ... #hematology
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... treatment #diagnosis #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... Management #Diagnosis #Hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... differential #diagnosis #hematology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Causes of Acquired Platelet Dysfunction

#Acquired #Platelet #Dysfunction #Causes #differential #Diagnosis #hematology
Causes of Acquired Platelet ... #Acquired #Platelet ... differential #Diagnosis #hematology
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
diphosphate; PF-3, platelet ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... → Refer to hematology ... • Nonmalignant hematologic ... Thrombocytosis #Platelets ... Diagnosis #Algorithm #hematology