22 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Inflammatory mechanism of asthma ... cytokines such as IL ... -5 and IL-1 3, which ... #asthma #pathophysiology
LABA/ICS Combination Inhalers
Long-Acting Beta2 Agonists (LABA) + Inhaled Corticosteroid (ICS) - Commonly used in Asthma 
Advair
Commonly used in Asthma ... (see one of my old ... that is dosed 1 ... Naming #Names #Pharmacology ... #Asthma
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
children with mild ... symptoms, may consider ... 2 puffs < 1 ... 4 puffs ≥ 1 ... Epinephrine #dosing #pharmacology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... at > 17 years old ... 2 settings - Symptoms ... than females (4:1) ... BehavioralDisorder #Pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Antibodies: Anti-Jo-1, ... Demographics: - F:M, 2:1 ... dehydrogenase (LD ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage 1: ... Mild/vasoconstrictive ... #Retinopathy #pathophysiology ... diagnosis #signs #symptoms
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
failure to thrive • Ill ... musculoskeletal symptoms ... Psychiatric symptoms ... Supplementation with 1 ... #AscorbicAcid #Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... Multi-system illness: 1. ... Findings: - Mild ... Possible DIC - Mild
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
gradually with symptoms ... including: 1. ... : Interstitial pneumonitis ... Exclusion of other ILDs ... Improvement in symptoms