73 results
Interstitial Lung Diseases (ILD)
Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): 
 • Hypersensitivity pneumonitis, Farmer's lung, Bird
Lung Diseases (ILD ... Hypersensitivity pneumonitis ... • Radiation pneumonitis ... , Polymyositis-dermatomyositis ... Idiopathic Interstitial Pneumonias
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Hypersensitivity, Pneumonitis ... Polymyositis, Dermatomyositis ... BrighamChiefs #ILD
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
the disease and ILD ... increases and ILD ... prevalence of RP-ILD ... Phenotype 1 ... #rheumatology #
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
DM/PM : dermatomyositis ... ConnectiveTissueDiseases #ILD ... Table #Pulmonary #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... or plaques • Dermatomyositis ... gangrenosum • IBD ... differential #diagnosis #rheumatology
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
Nodular pattern 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Antibodies (MSAs) Dermatomyositis ... Anti-Synthetase Syndrome: Jo-1, ... clinical #diagnosis #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... Classic triad of ILD ... Myositis #diagnosis #rheumatology
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
nodular pattern. 1. ... Hypersensitivity pneumonitis ... : ill defined centrilobular ... Hypersensitivity pneumonitis ... bronchiolitis: ill
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Antibodies: Anti-Jo-1, ... Demographics: - F:M, 2:1 ... dehydrogenase (LD ... PM #Diagnosis #Pathophysiology