10 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... rash) • Heart, lung ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
increases and ILD ... anti-NXP2 Abs Lung ... Phenotype 1 ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... starting amiodarone treatment ... including: 1. ... Exclusion of other ILDs ... macrophages Treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... -1 inhibitors, IL ... inhibitors, and IL ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Giant dilated left atrium on Echocardiogram (a4c)
It belongs to a 92-year old lady with a history
MR was only mild ... sinus rhythm... 1. ... Long chronic severe ... Echocardiogram #clinical #cardiology ... #pocus
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... • Interstitial Pneumonitis ... MALT Lymphoma • Lung ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
Dermatomyositis: • ILD ... positive patients Treatment ... Prednisone at 1 ... diagnosis #management #rheumatology ... #dermatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
trauma (> 65 years old ... disease states 1. ... Acute Pseudogout: Treatment ... ≥2 attacks • Long-term ... Deposition #Disease #Rheumatology
Authors: Mark M. Ramzy, DO, EMT-P (@MarkRamzyDO, EM Resident Physician, Drexel University, Department of Emergency Medicine)
This post will focus ... /50 Rule (part 1) ... and second ribs.1 ... #Radiology #CTChest ... #Lung #Pulmonary