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diagnosis management rheumatology activation amiodarone antinxp2 antinxp2dm cll common cvid dermatomyositis differential erythematosus hemeonc hemophagocytic hlh hypogammaglobulinemia immunodeficiency immunology induced
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... Rheumatic pain Clinical ... and lower jaw Treatment ... -1 inhibitors, IL ... diagnosis #management #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... Clinical Presentation ... Fever is the main clinical ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... to 8 years Clinical ... Autoimmunity • Chronic ... hypogammaglobulinemia #immunology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... CLL Labs: 1. ... microglobulin Treatment ... workup #oncology #hematology
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
respiratory distress syndrome ... • Chronic toxicity ... (e.g., chronic ... including: 1. ... Exclusion of other ILDs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... with Lupus: • Chronic
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Domestic and wild ... Lady Windermere Syndrome ... : • Syndrome of ... patients such as: 1. ... Hematologic malignancy
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
or the anterior chest ... auricular papules Clinical ... positive patients Treatment ... Prednisone at 1 ... #dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... dysfunction. 1. ... hyperinflammatory syndrome ... Clinical Presentation ... Diagnosis #Management #Hematology
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