13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... gangrenosum • IBD ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
1) Inflammatory ... joint pain (especially ... and fingers, or pain ... #diagnosis #sle ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... pneumonitis • ... pain • Swan neck ... • ANA titers > 1: ... #Rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
AM stiffness, >1 ... pain / swelling ... : CLINICAL DIAGNOSIS ... Certolizumab, Golimumab), IL ... #management #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... lasting > 30 mins - 1 ... arthritis • SLE ... #Diagnosis #MSK ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... Diagnosis: ... -1 inhibitors, IL ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... CRP level: (1) ... as opposed to 1 ... , and low back pain