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diagnosis management hematology rheumatology activation algorithm amiodarone cancer differential dress hemeonc hemophagocytic hlh immune induced inflammatory iris lung lymphohistiocytosis macrophage
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... respiratory distress syndrome ... including: 1. ... Exclusion of other ILDs ... macrophages Treatment
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
withdrawal • Mild ... treatment • Severe ... disease: 1. ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... -1 and IL-6, leading ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... worsening of that disease ... within the first 1 ... decrease in HIV-1 ... Drug reaction/ART toxicity
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... : • 10%-15% Pulmonary ... • Interstitial Pneumonitis ... Adenocarcinoma Treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO syndrome is ... and lower jaw Treatment ... osteoarticular and skin disease ... -1 inhibitors, IL ... diagnosis #management #Dermatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... cardiovascular or pulmonary ... risk of organ toxicity
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... hyperinflammatory syndrome ... ▪ Autoimmune diseases ... Treatment Approach ... Diagnosis #Management #Hematology
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