14 results
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
of Interstitial Lung ... this should be 1° ... Chronic Radiation Pneumonitis ... Amy Chung, MD, MSc ... #Diseases #ILD
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
Splint: Posterior long ... if types I or Ill ... followup within 1 ... • Nonoperative managernent ... Orthopedics #Proximal #MSK
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
increases and ILD ... anti-NXP2 Abs Lung ... Phenotype 1 ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL ... -1 and IL-6, leading ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... • Chronic lung ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... including: 1. ... Exclusion of other ILDs ... Pulmonary #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
-1 inhibitors, IL ... inhibitors, and IL ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Interstitial Pneumonitis ... phenomenon (16%) MSK ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Related Acute Lung ... 100,000,000, HCV 1 ... 2,000,000, HTLV 1 ... Transfusion #diagnosis #management ... #hematology #reactions