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diagnosis hematology syndrome activation amiodarone antinxp2 antinxp2dm causes common cvid dermatomyositis differential diseases hypogammaglobulinemia immunodeficiency immunology induced macrophage mas pulmonary
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Differential Diagnosis Algorithm ... this should be 1° ... Chronic Radiation Pneumonitis ... Amy Chung, MD, MSc ... #ILD #Causes #Differential
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... Direct cytotoxic lung ... including: 1. ... Exclusion of other ILDs ... Pulmonary #diagnosis #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... • Chronic lung ... Granulomatous lymphocytic interstitial ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Pneumonitis (LIP ... phenomenon (16%) MSK ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL ... -1 and IL-6, leading ... rash) • Heart, lung ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Dermatomyositis: • ILD ... Prednisone at 1 ... Dermatomyositis #diagnosis #management ... #rheumatology # ... dermatology
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