12 results
diagnosis rheumatology differential lupus druginduced hemeonc hemophagocytic hlh lymphohistiocytosis sle summary treatment anesthesia bleeding bruising cardiacarrest checklist comparison cop cryptogenic
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
pneumonia • formerly BOOP ... Unknown • 6-7 cases ... Pneumonia #COP #BOOP ... #pulmonary #ILD ... #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Prognosis: Usually mild ... Discontinuation of causal ... • Immunologic Workup ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
of SLE versus DIL ... • Immunologic Workup ... Positive in 60-80% of cases ... of SLE • Evolution ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
cytokines (TNFa,lL1, IL6 ... Auto-amplification loop ... Fibrinogen level, ↑ sIL ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... efficacious include IL ... -1 inhibitors, IL ... inhibitors, and IL ... diagnosis #management
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... Prognosis: Usually mild ... • Evolution: ... #rheumatology # ... diagnosis #treatment #management
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
senior on-call / dial ... delegate task of evaluating ... #Differential #Anesthesiology ... Checklist #Diagnosis #Management ... #Workup
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
von Willebrand syndrome ... administration, evaluation ... Acquired: • Mild ... discern these causes ... Differential #Diagnosis #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... • Interstitial Pneumonitis ... • Nephrogenic DI ... Hematologic: ... Diagnosis #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... globulin gap (>4 g/dL ... first step in evaluation ... changes (POEMS syndrome ... gastric tumors • Hematology
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