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differential management pulmonary fungal infectiousdiseases abscess acute algorithm amiodarone aspergillus betadglucan biomarkers causes chronic cough criteria diseases eosinophilia eosinophilic erythematosus
Cough - Diagnostic Schema Infectious: URTI, LRTI, Bacterial, Viral Irritant/Exposure: Allergic, Post-infectious, Pneumonitis, ACEi, PTX, Foreign Body Airway Disease:
Cough - Diagnostic ... , Pneumonitis, ACEi ... GERD, Dysphagia, CHF ... Autoimmune Vasculitis, ILD ... Malignancy: Lung
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... polymicrobial infection ... pneumonia • DM risk ... Pneumonitis 3. ... hemorrhage • Treatment
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... Hx of asthma, CF ... , CNS, skin • Infectious ... #differential #diagnosis ... #comparison #table
Tuberculin Skin Test Interpretation - Threshold for treatment Induration cutoff >5mm: • Recent exposure to an individual
Threshold for treatment ... consistent with old ... employees in high risk ... carcinoma of head/neck/lung ... SkinTest #TST #diagnosis
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Domestic and wild ... Food products Risk ... massiliense in CF ... Diagnosis Of NTM ... #differential #diagnosis
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced Lung ... starting amiodarone treatment ... failure - Infectious ... Exclusion of other ILDs ... macrophages Treatment
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
invasive fungal infection ... useful in high risk ... setting of GVHD) ID ... Galactomannan #diagnosis ... #comparison
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... fibromyalgia) • Infections ... • Acute lupus pneumonitis ... Thrombosis highest risk ... Erythematosus #Diagnosis
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
MUCORMYCOSIS • Risk ... Encapsulated yeast • At risk ... MC: CNS CSF: • ... change in the lungs ... nails, bronchi, lungs
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