773 results
Pathogenesis of PLA2R-associated (primary) Membranous Nephropathy

Immune deposits  → Activate complement  → C5b-9 complex
C5b-9 complex → Podocyte ... #Nephropathy #pathophysiology
Innate Immune Cells - Pathophysiology
The innate immune system consists of granulocytes, mast cells, natural killer cells,
Immune Cells - Pathophysiology ... killer cells, and monocytes ... Monocytes and neutrophils ... Monocytes and B-cells ... Immune #Cells #Pathophysiology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Nephrotic yndrome—podocyte ... 10 (eg direct podocyte ... damage) or 20 (podocyte
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
• Injury to podocytes
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
Codocytes (Target ... #Blood #Smear #Codocytes
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... (neutrophils, monocytes ... Fever #Fever #Pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... : Neutrophils, Monocytes ... Rigors #Bacteremia #Pathophysiology
Podocytopathies - Differential Diagnosis Algorithm

No podocytopenia - EM shows minimal change disease
 • Minimal Change Nephropathy
Podocytopenia
• FSGS NOS Podocyte ... Podocytopathy #podocytes
Characteristics of Selected Pneumonias

Streptococcus pneumoniae (pneumococcus). Gram-positive diplococci. 
Haemophilus influenzae. Pleomorphic gram-negative coccobacilli. 
Staphylococcus aureus. Plump
PMNs and monocytes