159 results
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... Peripheral Smear ... dysplastic erythroid precursors ... • Aplastic Anemia ... smear • Bone marrow
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Megaloblastic Anemia ... #Peripheral #Blood ... #Smear #Analysis
The arrows point to blister cells. These cells are thought to be precursors of helmet cells.
thought to be precursors ... Path #BloodSmear #Blood ... #Smear #BlisterCells
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... Path #BloodSmear #Blood ... #Smear #Elliptocyte
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... Path #BloodSmear #Blood ... #Smear #Dacrocytes
Megaloblastic Anemia vs Normal Peripheral Smear

#Megaloblastic #Anemia #Peripheral #Smear #Comparison #Clinical #Hypersegmented #Neutrophil
Megaloblastic Anemia ... Normal Peripheral Smear ... Megaloblastic #Anemia ... #Peripheral #Smear
Plasmodium Falciparum Gametocytes on Blood Smear.

Banana-shaped gametocytes are only seen in Plasmodium falciparum but rare in
Gametocytes on Blood ... Smear. ... falciparum but rare in blood ... smears - don't ... #Smear.
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... arrow) Peripheral smear ... Hematology #Pathology #Smear
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Diagnosis Algorithm Blood ... Normochromic RBCs on Smear ... • Anemia of Chronic ... Spherocytes on Smear