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diagnosis syndrome clinical hepatology neurology radiology symptoms aflp als amyotrophic arthritis biliary buckethandle caudaequina cholangitis cirrhosis differentiation fatty gout gouty
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... endothelial damage Prophylaxis ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... suspected, immediate MRI ... CaudaEquina #Syndrome #MSK ... #pathophysiology
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gouty Arthritis) - MSK ... mass and NO prior signs ... - **MSK rads ... Differential diagnosis ... #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
sclerosis Pathophysiology ... - Causes progressive ... MRI: Brain, cervical ... conditions listed in differential ... neurology #diagnosis #management
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... leukapheresis - TLS prophylaxis ... TLS #diagnosis #management ... #hematology
Medial Meniscus Bucket Handle Tear - MSK Radiology Imaging Findings: • Truncation of the medial meniscus on
Handle Tear - MSK ... The "double PCL sign ... Differential diagnosis ... posterior horn lateral ... BucketHandle #Tear #knee #mri
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Hyperreflexia develops later ... signs and/or symptoms ... Myelitis #diagnosis #management ... #neurology #differential
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... anterior/posterior MSK ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential
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