30 results
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Syndrome Step ... hematuria and/or proteinuria ... /nephritic syndromes ... dysmorphic RBCs in urine ... #Syndrome #Comparison
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... Nephrotic yndrome—podocyte ... #Nephrotic #Syndromes
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Syndrome and Nephritic ... Syndrome == Nephrotic ... - Normal/low Proteinuria ... #Syndrome #Nephritic ... #Comparison #Table
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... RBC casts, +/- proteinuria ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... , malignant HTN
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
membrane; GN = glomerulonephritis ... hemolytic-uremic syndrome ... arbitrarily defined as urine ... urine sediment ... #nephrotic #syndrome
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... range) proteinuria ... • Lupus glomerulonephritis
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary
CLINICAL
 • Nephritic syndrome (Casts)
 • Marked proteinuria (may be
Staphylococcus-associated GlomeruloNephritis ... CLINICAL • Nephritic ... syndrome (Casts ... ) • Marked proteinuria ... (may be nephrotic
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
Nephrotic-range ... Urine total protein ... The presence of nephrotic ... is defined as nephrotic ... syndrome
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... Red blood cell - Glomerulonephritis ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... syndrome ("Maltese
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24-hour urine ... So, proteinuria ... Serum or urine for ... workup #diagnosis #glomerulonephritis ... #nephrotic #nephritic