5914 results
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
Sclerosing Cholangitis (PSC ... ) PSC is a chronic ... • COVERT - PSC ... asymptomatic at diagnosis ... #Cholangitis #diagnosis
Primary sclerosing cholangitis (PSC) - Malignancy Screening and Surveillance Recommendations 

Cholangiocarcinoma 
 - Annual US or
sclerosing cholangitis (PSC ... Colonoscopy @ diagnosis ... #cholangitis #PSC ... Gastroenterology #Management #Diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... Transaminitis #Algorithm #diagnosis
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
- Differential Diagnosis ... pancreatitis, PSC ... (or secondary SC ... #differential #diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Differential #Diagnosis
Causes of Fat Malabsorption - Differential Diagnosis
Biliary Duct Obstruction
 • Autoimmune— PBC, PSC
 • Infection— liver
- Differential Diagnosis ... • Autoimmune— PBC ... , PSC • Infection ... #Differential #Diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Bile Ducts • PSC ... #Differential #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
- Differential Diagnosis ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Differential #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... #differential #diagnosis
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
pathophysiology #pbc ... #psc #hepatology