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hematology differential disease hemolytic oncology agglutinin aplastic causes extravascular incomplete intravascular kawasaki management mentzerindex monoclonal paraproteinemias pediatrics rdw reticulocyte reticulocytes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... anemia • ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold ... #Diagnosis #Algorithm
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... Diagnosis: • hemolytic ... anemia • Cold ... #anemia #hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is ... well as varying clinical ... The etiology of pancytopenia ... These causes could
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
bone marrow + pancytopenia ... Clinical Presentation ... • Peripheral Pancytopenia ... #oncology #hematology ... #diagnosis #management
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach to Anemia ... - Differential Diagnosis ... hyper-proliferative 2) Exclude hemolysis ... ) 3) Use MCV & clinical ... #hematology #algorithm
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Infants ≤6 months old ... if they have no clinical ... Albumin ≤3.0 g/dL, anemia ... purposes of this algorithm ... #Diagnosis #Peds
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