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management blood coagulation product reactions anticoagulant anticoagulation apixaban bruising causes clot dabigatran differential disseminated edoxaban hemostasis heparin inhibitor intravascular models
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #Coagulation #diagnosis ... treatment #management #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... and endothelial cells ... #clot #PT #PTT ... #diagnosis #models ... #hematology #pathophysiology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... integrity Clotting cascade ... disease • Acute DIC ... warfarin, direct thrombin ... #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... coagulopathy & ↑bleeding ... RBCs (stored at 4C ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... coagulopathy & ↑bleeding ... RBCs (stored at 4C ... #Transfusions #diagnosis ... #management #hematology
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