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coagulation diagnosis abnormal anticoagulant anticoagulation apixaban aptt cascade dabigatran dic differential heparin inhibitor intravascular management models pathophysiology pathway platelet prolonged
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
Thrombin, then primes ... and endothelial cells ... #clot #PT #PTT ... diagnosis #models #hematology ... #Rivaroxaban #Edoxaban
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Rivaroxaban, apixaban, edoxaban ... drugs e.g. direct thrombin ... Disseminated intravascular ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... • Increased thrombin ... significant fibrin clot ... treatment #management #hematology
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