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diagnosis blood hepatology product reactions treatment causes chemistry coagulation dic differential disseminated hepatopulmonary interpretation intravascular leukostasis lfts liver lysis rvalue
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis of tumor cells ... lethargy, hematuria, cardiac ... with tetany or cardiac ... TLS #diagnosis #management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... causes #treatment #management ... #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Coagulation factors: PT ... Skeletal muscle, cardiac ... Skeletal muscle, Cardiac ... • Gilbert's syndrome ... #differential #Hepatology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... left heart 3-6 cardiac ... Arterial blood gas (ABC ... hepatopulmonary #syndrome ... #treatment #hepatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Transfusion Cardiac ... potassium from lysed cells ... RBCs (stored at 4C ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Transfusion Cardiac ... potassium from lysed cells ... RBCs (stored at 4C ... Transfusions #diagnosis #management ... #hematology #reactions
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