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diagnosis hematology causes differential abnormal aptt cardiac cardiology clinical echocardiogram pocus prolonged anticoagulant anticoagulation apixaban bleeding bruising cascade clot dabigatran
Amyloidosis on POCUS Echocardiogram - Apical 4 Chamber (A4C) Pt with systemic AL amyloidosis presents with 1
Apical 4 Chamber (A4C ... ) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... Echocardiogram #Cardiology #A4C
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 The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... Thrombin, then primes ... and endothelial cells ... #Coagulation #Cascade ... #clot #PT #PTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... with systemic amyloidosis ... differential #hematology #coagulation
Amyloidosis on POCUS Echocardiogram - Subcostal 4 Chamber (S4C) Pt with systemic AL amyloidosis presents with 1
Subcostal 4 Chamber (S4C ... ) Pt with systemic ... Pt has biventricular ... Has new large pericardial ... Echocardiogram #Cardiology #S4C
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 Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... with systemic amyloidosis ... differential #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Schistocytes, helmet cells
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... intravascular coagulation ... warfarin, direct thrombin ... or factor X • Amyloidosis-associated ... Vasculitis • Amyloidosis
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