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diagnosis hematology causes differential abnormal aptt bleeding bruising hemostasis intravascular management treatment
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... Disseminated intravascular ... coagulation (DIC ... differential #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... Coagulation (DIC ... Thrombocytopenia • Prolonged ... PT/PTT • Low ... • Increased thrombin
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and aPTT If ... drugs (e.g. direct thrombin ... hemorrhage • Disseminated ... intravascularcoagulation (DIC ... differential #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... prolonged after ... liver failure, disseminated ... disease • Acute DIC ... warfarin, direct thrombin
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