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diagnosis hematology abnormal aptt prolonged blanching bleeding bruising dic ecchymosis hematomas hemostasis intravascular management petechiae purpura thrombocytopenia treatment
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... drugs (e.g. direct thrombin ... hemorrhage • Disseminated ... #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... #diagnosis #causes
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... drugs e.g. direct thrombin ... Disseminated intravascular ... coagulation (DIC ... #diagnosis #differential
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... gums can also arise ... liver failure, disseminated ... discern these causes ... warfarin, direct thrombin
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Bruise (also called ... ecchymosis) is caused ... in endothelial cells ... to be normal, PT ... VWF:RCo/VWF:Ag (differentiate
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