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hematology coagulation differential causes clinical clots echocardiogram mcconnells pocus prolonged anticoagulant apixaban bleeding bruising cascade clot dabigatran edoxaban embolism heparin
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... 3 d later with normal ... Echocardiogram #A4C
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 Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
strain, McConnell sign ... BP is normal and ... pt not in distress ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... PT/ABNORMAL PTT ... warfarin, direct thrombin
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
PT and/or aPTT ... Congenital intrinsic ... drugs e.g. direct thrombin ... #PT #aPTT #Prolonged ... #Causes #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
PT and the aPTT ... affected in the intrinsic ... drugs (e.g. direct thrombin ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... pathophysiology #anticoagulation
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