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hematology coagulation causes differential abnormal anticoagulation apixaban bleeding bruising cascade clot dabigatran dic disseminated edoxaban hemostasis heparin inhibitor management models
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
heparin - Other anticoagulants ... Congenital intrinsic ... drugs e.g. direct thrombin ... Disseminated intravascular ... #Causes #diagnosis
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... Abnormality in the intrinsic ... , disseminated intravascular ... pathway to the intrinsic ... warfarin, direct thrombin
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
along with FXIIa (intrinsic ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Disseminated Intravascular ... • Prolonged PT ... • Increased thrombin ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
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