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hematology anticoagulation coagulation aptt causes abnormal anticoagulant cascade clot dabigatran dic differential disseminated doac effects heparin inhibitor intravascular management models
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Coagulation Tests PT ... Clotting Time, Thrombin ... Rivaroxaban Apixaban ... , Edoxaban Argatroban ... #Diagnosis #Laboratory
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant ... #inhibitor #Apixaban ... #Rivaroxaban #Edoxaban
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... , rixaroxaban, apixaban ... and edoxaban. ... clotting time; TT = thrombin ... #testing #aptt
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
- Rivaroxaban, apixaban ... , edoxaban (typically ... heparin - Other anticoagulants ... drugs e.g. direct thrombin ... Prolonged #Causes #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Increased thrombin ... venipuncture sites Laboratory ... significant fibrin clot ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
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