523 results
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
Calcium Channel ... : No effect • Dromotropy ... Chronotropy: Slows • Dromotropy ... CCBs #Calcium #Channel
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Depolarization: • Na+ channels ... Phase • Ca++ channels ... Potential: • K+ channels ... CLASS 1 - Sodium Channel ... Block fast Na+ channels
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
agents - Sodium Channel ... agents - Potassium Channel ... agents - Calcium Channels
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
CLASS 1 - Sodium Channel ... Block fast Na+ channels ... 3 - Potassium Channel ... MOA: Block K+ channels ... Block slow Ca++ channels
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
cotransporter, K channel ... , Cl channel, or ... barrtin (recruits Cl channel ... epithelial sodium channels ... epithelial sodium channels
Mean Arterial Pressure (MAP)

Average arterial pressure throughout one cardiac cycle, systole, and diastole. 
Surrogate indicator of
the chronotropy, dromotropy ... #chronotropy #dromotropy ... #lusitropy #Pulsepressure
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
to the sodium-channel ... voltage-sensitive calcium channels
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... Antiarrhythmics #Sodium #Channel
Dihydropyridine Calcium Channel Blockers

Mechanism of Action:  L-Type calcium channel blockade - Inhibits the influx of
Dihydropyridine Calcium Channel ... L-Type calcium channel ... Dihydropyridine #Calcium #Channel
Pharmacologic Treatments of Chronic Hypertension in Pregnancy
Central alpha-agonists
 - Methyldopa
 - Clonidine
Combined alpha- and beta-blocker
 -
Non-dihydropyridine Calcium Channel ... Dihydropyridine Calcium Channel