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Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Mucocutaneous lymph node syndrome ... • Progressive symptoms ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... hyperimmunoglobulin D syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... scleritis • Palpable
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... • Cutaneous: palpable ... purpura 2/2 vasculitis ... Pulmonary #Renal #Syndromes
An Approach to the Unknown Rash: Petechial-Purpuric Rash 
#Diagnosis #Dermatology #Petechial #Purpura #Purpuric #Rash #Palpable #Algorithm
Rash: Petechial-Purpuric ... Dermatology #Petechial #Purpura ... #Purpuric #Rash ... #Palpable #Algorithm ... #Differential #
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
with devastating differential ... the etiology of palpable ... Palpable (raised ... , the differential ... #Nonpalpable #Differential
Palpable Purpura - Rash Algorithm
#Diagnosis #Dermatology #Rash #Palpable #Purpura #Differential #Algorithm
Palpable Purpura ... Dermatology #Rash #Palpable ... #Purpura #Differential
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... - Differential ... → Palpable • ... BrighamChiefs #Purpura ... #Causes #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... CAUSES OF NON-PALPABLE ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Differential #
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... - Differential ... C), Pigmented purpuric ... #nonpalpable #palpable ... #Causes #Differential