11 results
diagnosis management rheumatology oncology dermatology differential hemophagocytic lymphohistiocytosis activation chronic classification cll dress endocarditis infections infectiousdiseases intermittent leukemia lymphocytic lymphoma
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
of about three cases ... • Dyspnea • Fever ... number of sites of disease ... Lymphoma Treatment ... classification #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Hemopathies+++: Hodgkin ... • Autoimmune diseases ... Adult-onset Still disease ... Treatment: •
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Intermittent tertian: P. vivax ... Non-Infectious Causes ... • Behcet's syndrome ... • Hyper-IgD syndrome ... 1-2 weeks • Hodgkin
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... • Periodic fever ... • HLH Labs: ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... Lymphadenopathy • Fevers ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
characterized by fever ... with systemic disease ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Fever >38.5 2. ... : symptomatic treatment ... • Severe disease ... SinaiBmoreIMRes #DRESS #Syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... Adenocarcinoma Treatment
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
night sweats, fever ... Cholesterol emboli syndrome ... Septic emboli cause ... hematuria, + RF Treatment ... Differential #Diagnosis #cardiology
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