11 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... confirmed the diagnosis ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Management Summary Causes ... Heat injury, Heat stroke ... Dermatomyositis Clinical ... #Management #causes
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Sedation Scale (RASS ... will vary with clinical ... , bradycardia. renal ... dissociative drug, it causes ... #CriticalCare #diagnosis
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
virus • CMV • EBV ... Maculopapular rash ... • Common clinical ... meningovascular (stroke ... • Uveitis • Rash
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study
Clinical Trial of ... NEJM 2018 https ... TessaRDavis #EBM ... VisualAbstract #Peds ... Infusion #Rates #NEJM
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents, Renal ... Constipation, Seizures, Stroke ... the underlying cause ... Seizures: Treat with AEDs ... until cause identified
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
sawtooth rete pegs ... confirming the diagnosis ... Although the cause ... #NEJM #clinical ... lichen #planus #derm
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... responsible for most cases ... loss • Skin: Rash ... meningovascular disease, or stroke ... Syphilis #stages #diagnosis
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... during Delivery • Stable ... teratogenic GDMT meds ... Serial TTE and close
Clinical Manifestations of Sickle Cell Disease

Anaemia
Infection
Painful crises
Priapism
Splenomegaly
Long Term Problems - Short stature and delayed puberty, Stroke
Clinical Manifestations ... Splenomegaly Long Term ... delayed puberty, Stroke ... Heart failure, Renal ... Signs #Symptoms #Diagnosis