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management lupus summary antinxp2 antinxp2dm comparison derm dermatology dermatomyositis dil erythematosus granuloma hemophagocytic hlh lichen lymphohistiocytosis majocchis microscopy rubrum sjogrens
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... life-threatening • Treatment ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... Treatment: • ... #summary #rheumatology
Lichen Planus- ...On examination, numerous purple papules were noted on the anterior surface of the forearms
sawtooth rete pegs ... confirming the diagnosis ... used in primary treatment ... #NEJM #clinical ... #photo #lichen #
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary and lacrimal glands ... overlaps with RA, SLE ... salivary ducts Clinical ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Violaceous papules or plaques ... auricular papules Clinical ... Muscle atrophy may cause ... positive patients Treatment ... #management #rheumatology
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
/ foot + tinea pedis ... Treatment: Itraconazole ... tissues - mainly caused ... nodules, papules, plaques ... #photo #microscopy
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